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Oral Formulation Roadmap from Early Drug Discovery to Development

Elizabeth Kwong

Medical / Pharmacology

Detailing formulation approaches by stage of discovery to early development, this book gives a "playbook" of practical and efficient strategies to formulate drug candidates with the least chance of failing in clinical development. Comes from contributing authors with experience developing formulations on the frontlines of the pharmaceutical industry. Focuses on pre (or non- ) clinical and early stage development, the phases where most compounds are used in drug research. Features case studies to illustrate practical challenges and solutions in formulation selection. Covers regulatory filing, drug metabolism and physical and chemical properties, toxicology formulation, biopharmaceutics classification system (BCS), screening approaches, early stage clinical formulation development, and outsourcing.
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