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Genetic and Environmental Factors in Rheumatic Diseases

Hai-Feng Pan , Jindong Ni , Jing Ni , Wenbiao Hu , Zhiwei Xu

Medical / General

Rheumatic diseases are a group of diseases that cause varying degrees of disability, involving bones, joints, muscles and surrounding soft tissues. In the last two decades, increasing research on rheumatic diseases has been conducted. Nevertheless, the etiology and pathogenesis of these diseases have not been fully elucidated. It is generally recognized that the onset and development of rheumatic diseases are the result of a combination of multiple factors, such as genetic, environmental and immune abnormalities, etc. Among these factors, the influence of immune abnormalities in rheumatic diseases has been extensively explored in depth nowadays. Moreover, as the influence of genetic and environmental factors on public health is gaining more attention, studies on the role of these two types of factors in rheumatic diseases have become an important direction.
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