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Forensic Genetic Approaches for Identification of Human Skeletal Remains
Challenges, Best Practices, and Emerging Technologies
Angie Ambers
Unidentified human remains are often associated with tragic events, such as fires, terrorist attacks, natural disasters, war conflicts, genocide, airline crashes, homicide, and human rights violations under oppressive totalitarian regimes. In these situations, extensive damage to soft tissues often precludes the use of such biological samples in the identification process. In contrast, bone material is the most resilient, viable sample type for DNA testing. DNA recovered from bone often is degraded and in low quantities due to the effects of human decomposition, environmental exposure, and the passage of time. The complexities of bone microstructure and its rigid nature make skeletal remains one of the most challenging sample types for DNA testing.
- Provides best practices on processing bone samples for DNA testing
- Presents detailed coverage of proper facilities design for skeletal remains processing, selection of optimal skeletal elements for DNA recovery, specialized equipment needed, preparation and cleaning of bone samples for DNA extraction, and more
- Highlights complementary disciplines often used in concert with genetic data to make positive identifications, such as forensic anthropology, forensic odontology, and forensic art/sculpting
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