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Diabetes

Chapter 2. Cerebral Ischemia in Diabetics and Oxidative Stress

Kunjan R. Dave , Miguel A. Perez-Pinzon , Perry Fuchs

Medical / Nursing / Nutrition

Cerebral ischemia is one of the major complications of diabetes. Eighty four percent of diabetics die from either heart disease or stroke (both cause cerebral ischemia). Diabetes-induced oxidative stress is one of the factors responsible for the secondary complications of diabetes. Oxidative stress also plays a key role in cerebral ischemic damage. In this chapter we provide a literature review of how cerebral ischemia-induced oxidative stress is exacerbated in diabetics. We also provide correlates of how this increased oxidative stress may be responsible for increased cerebral ischemia damage in diabetics.
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