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The Biology of the Autistic Syndromes

Christopher Gillberg , Mary Coleman

Medical / General

This new edition of the biology of the Autistic Syndromes provides a comprehensive update on recent advances in this rapidly developing field. It is designed for use by physicians who diagnose and treat people with an autistic spectrum disorder. Clinical diagnosis is facilitated by full discussion and clear guidelines for infancy, childhood, adolescence and adulthood. Autism is not a single disease entity but rather a syndrome f different diseases. Some of these diseases were discovered in studying patients with autism ; others are a subgroup of cases within an already established diseases such as tuberous sclerosis. Many of these diseases are genetic, and the book gives up-to-date information on what is know about molecular biology and autism. Persons with autism may also have a seizure disorder (as did two of the original eleven patients described by Kanner) - a chapter is dedicated to epilepsy and electrophysiological studies. Aspreger syndrome is the subject of a separate chapter. Epidemiology, neutopsychological studies and behaviour complexes, such as self-injury, are reviewed in detail. Other sections cover biochemistry, endocrinology, immunology, brain imaging and neuropathology. Chapters are devoted to the medical evaluation of patients, including diagnostic aids, and to available medical therapies as well as what is known about other interventions such as psychoeducational and behavioural modification procedures. Finally, knowledge from diverse fields is integrated in a chapter on the neurology of autism.
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